
I am doing further research on the subject of repairing the body on a cellular level and the how fasting can play a huge role in it. Today I will see…
Fasting, Weight Loss, and Autophagy
Your health is always in your hands 😀

I am doing further research on the subject of repairing the body on a cellular level and the how fasting can play a huge role in it. Today I will see…
Fasting, Weight Loss, and Autophagy

Alternate-day fasting involves alternating fasting days, during which no calories are consumed, and feeding days, during which foods and beverages are consumed ad libitum.
In 2007, Varady & Hellerstein (111) reviewed alternate-day fasting studies in rodents and concluded that this fasting regimen was as effective as simple caloric restriction in reducing obesity-associated body weight and fasting insulin and glucose concentrations.
Various studies show that ADF:-

ADF has also shown to:-
The sparse data on alternate-day fasting suggest that this regimen can result in modest weight loss and lead to improvements in some metabolic parameters.
Although ADF has shown to improve health and metabolic markers but it seems difficult to consider it as a lifestyle change. Because it has very strict time restrictions, it is difficult for most of the people to follow it consistently. As you know, consistency is the key in any weight loss journey, not following it regularly may lead to eventual weight gain!

This it is suggested to follow an easier fasting schedule like 16:8, 18:6, 20:4 or even OMAD, so that you are able to stick to it!
Thankyou for giving your time!😇😇

Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer.
“Auto” means self and “phagy” means eat. So the literal meaning of autophagy is “self-eating.”
It’s also referred to as “self-devouring.” While that may sound like something you never want to happen to your body, it’s actually beneficial to your overall health. This is because autophagy is an evolutionary self-preservation mechanism through which the body can remove the dysfunctional cells and recycle parts of them toward cellular repair and cleaning.
The main benefits of autophagy seem to come in the form of anti-aging principles. In fact, Petre says it’s best known as the body’s way of turning the clock back and creating younger cells.
Khorana points out that when our cells are stressed, autophagy is increased in order to protect us, which helps enhance your lifespan.
At the cellular level, the benefits of autophagy include:
Fasting is [the] most effective way to trigger autophagy”
Ketosis, a diet high in fat and low in carbs brings the same benefits of fasting without fasting, like a shortcut to induce the same beneficial metabolic changes. By not overwhelming the body with an external load, it gives the body a break to focus on its own health and repair.
In the keto diet, you get about 75 percent of your daily calories from fat, and 5 to 10 percent of your calories from carbs.
This shift in calorie sources causes your body to shift its metabolic pathways. It will begin to use fat for fuel instead of the glucose that’s derived from carbohydrates.
In response to this restriction, your body will begin to start producing ketone bodies that have many protective effects. Khorana says studies suggest that ketosis can also cause starvation-induced autophagy, which has neuroprotective functions. Low glucose levels occur in both diets and are linked to low insulin and high glucagon levels.
When the body is low on sugar through fasting or ketosis, it brings the positive stress that wakes up the survival repairing mode.
Autophagy will continue to gain attention as researchers conduct more studies on the impact it has on our health.
For now, nutritional and health experts such as Khorana point to the fact that there’s still much we need to learn about autophagy and how to best encourage it.
But if you’re interested in trying to stimulate autophagy in your body, she recommends starting by adding fasting and regular exercise into your routine.
However, you need to consult your doctor if you’re taking any medications, are pregnant, breastfeeding, or wish to become pregnant, or have a chronic condition, such as heart disease or diabetes.
Khorana cautions that you’re not encouraged to fast if you fall into any of the above categories.

Intermittent fasting is normally associated with weight loss and it is indeed a proven weight loss tool, as many have testified. But can it really improve your mental well-being too?
Yes, according to the research. It appears there are two ways in which intermittent fasting (IF) can exert positive effects on mood and cognitive function. The first is by increasing levels of a protein in the brain called brain-derived neurotrophic factor (BDNF). The second is by triggering a process called autophagy.
BDNF is a neuroprotective substance that increases resistance to damage and encourages the growth of new neurons.
Studies have shown that BDNF levels tend to be lower in people with depression, anxiety and major depressive disorder, and the lower levels are, the more severe the symptoms.
One of the ways that BDNF has been shown to enhance mood is by working in concert with the neurotransmitter serotonin. Some antidepressants – the selective serotonin reuptake inhibitors (SSRIs) – work by maintaining levels of serotonin in the brain. Serotonin and BDNF together act ‘cooperatively’ to enhance brain activity, and impaired signalling between these two substances is thought to be a core feature of depression and anxiety disorders.
Low levels of BDNF are also associated with various neurological disorders, including Alzheimer’s disease.
The association with Alzheimer’s disease is probably because BDNF is particularly active in the areas of the brain related to memory, especially the hippocampus.
A 2006 study found that ‘there is strong evidence that BDNF may contribute to the pathogenesis of several neuropsychiatric disorders such as Alzheimer’s disease (AD), affective disorders (AFDs), and posttraumatic stress disorder (PTSD).’
The second link between intermittent fasting and mental health is a process called autophagy. Discovered in 2016 by a Japanese cell biologist – who won a Nobel Prize for his efforts – autophagy is a remarkable process that the body uses to give itself what is essentially a good cleanout.
Meaning “self-eating” in Greek, autophagy is often likened to a form of cellular housekeeping. Each cell is capable of destroying or engulfing old or worn-out internal components and taking them to its waste disposal unit within the cell, called the lysosome.
Some of those components include damaged proteins and other debris that are “common features of neurodegenerative diseases”.
Consider autophagy to be a means of conducting quality control. By weeding out worn-out components, autophagy protects brain cells and slows the advancement of disease.
Fortunately for us all, autophagy is something that doesn’t require medication. All you have to do is stop eating.
When you do so, blood glucose is depleted, and insulin production stops. Insulin suppresses autophagy – when you take a break from eating, insulin declines and autophagy is triggered. Conversely, when you are busy eating and digesting, autophagy is put on hold: the cell is otherwise engaged.
A 2010 study discovered,“One well-recognized way of inducing autophagy is by food restriction.”
What’s more, you don’t have to starve yourself or become malnourished. A simple, short fast will suffice.
Fasting is normal for humans and not a passing fad. It’s what our hunter-gatherer ancestors did, in the absence of shops – they had to be able to make critical decisions and move fast on an empty stomach.

There are many different ways of intermittent fasting. The methods vary in the number of fast days and the calorie allowances.

The rules for this diet are simple. A person needs to decide on and adhere to a 12-hour fasting window every day.
This type of intermittent fasting plan may be a good option for beginners. This is because the fasting window is relatively small, much of the fasting occurs during sleep, and the person can consume the same number of calories each day.
The easiest way to do the 12-hour fast is to include the period of sleep in the fasting window.
For example, a person could choose to fast between 7 p.m. and 7 a.m. They would need to finish their dinner before 7 p.m. and wait until 7 a.m. to eat breakfast but would be asleep for much of the time in between.

Fasting for 16 hours a day, leaving an eating window of 8 hours, is called the 16:8 method or the Leangains diet.
During the 16:8 diet, men fast for 16 hours each day, and women fast for 14 hours. This type of intermittent fast may be helpful for someone who has already tried the 12-hour fast but did not see any benefits.
On this fast, people usually finish their evening meal by 8 p.m. and then skip breakfast the next day, not eating again until noon.

People following the 5:2 diet eat standard amounts of healthful food for 5 days and reduce calorie intake on the other 2 days.
During the 2 fasting days, men generally consume 600 calories and women 500 calories.
Typically, people separate their fasting days in the week. For example, they may fast on a Monday and Thursday and eat normally on the other days. There should be at least 1 non-fasting day between fasting days.

There are several variations of the alternate day fasting plan, which involves fasting every other day.
For some people, alternate day fasting means a complete avoidance of solid foods on fasting days, while other people allow up to 500 calories. On feeding days, people often choose to eat as much as they want.
Alternate day fasting is quite an extreme form of intermittent fasting, and it may not be suitable for beginners or those with certain medical conditions. It may also be difficult to maintain this type of fasting in the long term.

Fasting completely for 1 or 2 days a week, known as the Eat-Stop-Eat diet, involves eating no food for 24 hours at a time. Many people fast from breakfast to breakfast or lunch to lunch.
People on this diet plan can have water, tea, and other calorie-free drinks during the fasting period.
People should return to normal eating patterns on the non-fasting days. Eating in this manner reduces a person’s total calorie intake but does not limit the specific foods that the individual consumes.
A 24-hour fast can be challenging, and it may cause fatigue, headaches, or irritability. Many people find that these effects become less extreme over time as the body adjusts to this new pattern of eating.

The Warrior Diet is a relatively extreme form of intermittent fasting.
The Warrior Diet involves eating very little, usually just a few servings of raw fruit and vegetables, during a 20-hour fasting window, then eating one large meal at night. The eating window is usually only around 4 hours.
This form of fasting may be best for people who have tried other forms of intermittent fasting already.
Although it is possible to eat some foods during the fasting period, it can be challenging to stick to the strict guidelines on when and what to eat in the long term. Also, some people struggle with eating such a large meal so close to bedtime.
There is also a risk that people on this diet will not eat enough nutrients, such as fiber. This can increase the risk of cancer and have an adverse effect on digestive and immune health.
There are many different ways to do intermittent fasting, and there is no single plan that will work for everyone. Individuals will experience the best results if they try out the various styles to see what suits their lifestyle and preferences.
Regardless of the type of intermittent fasting, fasting for extended periods when the body is unprepared can be problematic.
These forms of dieting may not be suitable for everyone. If a person is prone to disordered eating, these approaches may exacerbate their unhealthy relationship with food.
People with health conditions, including diabetes, should speak to a doctor before attempting any form of fasting.
For the best results, it is essential to eat a healthful and balanced diet on non-fasting days. If necessary, a person can seek professional help to personalize an intermittent fasting plan and avoid pitfalls.

People have a tendency to makes us feel even more worse than we were before when we become ourselves. A flower bud sprouted excitedly above the ground to become a glorious beautiful bloom. It didn’t notice the dying flowers around it that once were glorious and beautiful. The flower bud missed the time when everyone […]
It’s Okay To Be You

Researchers have been studying intermittent fasting for decades.
Study findings are sometimes contradictory and inconclusive. However, the research on intermittent fasting, including 16:8 fasting, indicates that it may provide the following benefits:
Eating during a set period can help people reduce the number of calories that they consume. It may also help boost metabolism.
A 2017 study suggests that intermittent fasting leads to greater weight loss and fat loss in men with obesity than regular calorie restriction.
Research from 2016 reports that men who followed a 16:8 approach for 8 weeks while resistance training showed a decrease in fat mass. The participants maintained their muscle mass throughout.
In contrast, a 2017 study found very little difference in weight loss between participants who practiced intermittent fasting — in the form of alternate-day fasting rather than 16:8 fasting — and those who reduced their overall calorie intake. The dropout rate was also high among those in the intermittent fasting group.
Supporters of intermittent fasting suggest that it can prevent several conditions and diseases, including:
However, the research in this area remains limited.
A 2014 review reports that intermittent fasting shows promise as an alternative to traditional calorie restriction for type 2 diabetes risk reduction and weight loss in people who have overweight or obesity.
The researchers caution, however, that more research is necessary before they can reach reliable conclusions.
A 2018 study indicates that in addition to weight loss, an 8-hour eating window may help reduce blood pressure in adults with obesity.
Other studies report that intermittent fasting reduces fasting glucose by 3–6% in those with prediabetes, although it has no effect on healthy individuals. It may also decrease fasting insulin by 11–57% after 3 to 24 weeks of intermittent fasting.
Time-restricted fasting, such as the 16:8 method, may also protect learning and memory and slow down diseases that affect the brain.
A 2017 annual review notes that animal research has indicated that this form of fasting reduces the risk of nonalcoholic fatty liver disease and cancer.
Animal studies suggest that intermittent fasting may help animals live longer. For example, one study found that short-term repeated fasting increased the life span of female mice.
The National Institute on Aging point out that, even after decades of research, scientists still cannot explain why fasting may lengthen life span. As a result, they cannot confirm the long-term safety of this practice.
Human studies in the area are limited, and the potential benefits of intermittent fasting for human longevity are not yet known.
When you don’t eat for a while, several things happen in your body.
For example, your body changes hormone levels to make stored body fat more accessible and initiates important cellular repair processes.
Here are some of the changes that occur in your body during fasting:
Type 2 diabetes has become a very common diagnosis in recent decades.
Its main feature is high blood sugar levels in the context of insulin resistance.
Anything that reduces insulin resistance should help lower blood sugar levels and protect against type 2 diabetes.
Interestingly, intermittent fasting has been shown to have major benefits for insulin resistance and to lead to an impressive reduction in blood sugar levels.
In human studies on intermittent fasting, fasting blood sugar has been reduced by 3–6% over the course of 8–12 weeks in people with prediabetes. Fasting insulin has been reduced by 20–31%.
One study in mice with diabetes also showed that intermittent fasting improved survival rates and protected against diabetic retinopathy. Diabetic retinopathy is a complication that can lead to blindness.
What this implies is that intermittent fasting may be highly protective for people who are at risk for developing type 2 diabetes.
However, there may be some differences between the sexes. One 2005 study in women showed that blood sugar management actually worsened after a 22-day long intermittent fasting protocol.
Oxidative stress is one of the steps toward aging and many chronic diseases.
It involves unstable molecules called free radicals. Free radicals react with other important molecules, such as protein and DNA, and damage them.
Several studies show that intermittent fasting may enhance the body’s resistance to oxidative stress.
Additionally, studies show that intermittent fasting can help fight inflammation, another key driver of many common diseases.
It’s known that various health markers (so-called “risk factors”) are associated with either an increased or decreased risk of heart disease.
Intermittent fasting has been shown to improve numerous different risk factors, including:
However, much of this is based on animal studies
When we fast, the cells in the body initiate a cellular “waste removal” process called autophagy.
This involves the cells breaking down and metabolizing broken and dysfunctional proteins that build up inside cells over time.
Increased autophagy may provide protection against several diseases, including cancer and neurodegenerative diseases such as Alzheimer’s disease.

16:8 intermittent fasting, which people sometimes call the 16:8 diet or 16:8 plan, is a popular type of fasting. People who follow this eating plan will fast for 16 hours a day and consume all of their calories during the remaining 8 hours.
16:8 intermittent fasting is a form of time-restricted fasting. It involves consuming foods during an 8-hour window and avoiding food, or fasting, for the remaining 16 hours each day.
Some people believe that this method works by supporting the body’s circadian rhythm, which is its internal clock.
Most people who follow the 16:8 plan abstain from food at night and for part of the morning and evening. They tend to consume their daily calories during the middle of the day.
There are no restrictions on the types or amounts of food that a person can eat during the 8-hour window. This flexibility makes the plan relatively easy to follow.
The easiest way to follow the 16:8 diet is to choose a 16-hour fasting window that includes the time that a person spends sleeping.
Some experts advise finishing food consumption in the early evening, as metabolism slows down after this time. However, this is not feasible for everyone.
Some people may not be able to consume their evening meal until 7 p.m. or later. Even so, it is best to avoid food for 2–3 hours before bed.
People may choose one of the following 8-hour eating windows:
Within this timeframe, people can eat their meals and snacks at convenient times. Eating regularly is important to prevent blood sugar peaks and dips and to avoid excessive hunger.
Some people may need to experiment to find the best eating window and mealtimes for their lifestyle.
A balanced diet focuses primarily on:
Fruits, vegetables, and whole grains are high in fiber, so they can help keep a person feeling full and satisfied. Healthful fats and proteins can also contribute to satiety.
Beverages can play a role in satiety for those following the 16:8 intermittent fasting diet. Drinking water regularly throughout the day can help reduce calorie intake because people often mistake thirst for hunger.
The 16:8 diet plan permits the consumption of calorie-free drinks — such as water and unsweetened tea and coffee— during the 16-hour fasting window. It is important to consume fluids regularly to avoid dehydration.
People may find it easier to stick to the 16:8 diet when they follow these tips: